Article
Genome-wide identification of Sox8-, and Sox9-dependent genes during early post-natal testis development in the mouse.
Andrology - 1 Mar 2013
Chalmel F, Lardenois A, Georg I, Barrionuevo F, Demougin P, Jégou B, Scherer G, Primig M
Abstract excerpt
The SOX8 and SOX9 transcription factors are involved in, among others, sex differentiation, male gonad development and adult maintenance of spermatogenesis. Sox8(-/-) mice lacking Sox9 in Sertoli cells fail to form testis cords and cannot establish spermatogenesis. Although genetic and histologic...
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