Article
Genome-wide identification of Sox8-, and Sox9-dependent genes during early post-natal testis development in the mouse.
Andrology - 1 Mar 2013
Chalmel F, Lardenois A, Georg I, Barrionuevo F, Demougin P, Jégou B, Scherer G, Primig M
Abstract excerpt
The SOX8 and SOX9 transcription factors are involved in, among others, sex differentiation, male gonad development and adult maintenance of spermatogenesis. Sox8(-/-) mice lacking Sox9 in Sertoli cells fail to form testis cords and cannot establish spermatogenesis. Although genetic and histological data show an important role for these transcription factors in regulating spermatogenesis, it is not clear which...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
