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Article

Effects of PTEN gene alteration in patients with gallbladder cancer.

Cancer genetics - 1 Dec 2015

Ali Asgar, Mishra Pramod Kumar, Sharma Sadhana, Arora Asit, Saluja Sundeep Singh

Abstract excerpt

Gallbladder cancer (GBC) is an aggressive malignancy usually diagnosed in an advanced stage. We investigated the effects of alterations of the phosphatase and tensin homologue (PTEN) gene on the occurrence and development of GBC, which has not been previously reported. A total 141 cases of GBC were analyzed for mutation, expression, and methylation across the nine exons of the PTEN gene. DNA sequencing methods...

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Source

Identifiers

PMID: 26586294
DOI: 10.1016/j.cancergen.2015.09.007

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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