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Clinical significance of the mutational landscape and fragmentation of circulating tumor DNA in renal cell carcinoma

10 Dec 2018

Abstract excerpt

Reliable biomarkers for renal cell carcinoma (RCC) have yet to be determined. Circulating tumor DNA (ctDNA) is an emerging resource to detect and monitor molecular characteristics of various tumors. The present study aims to clarify the clinical utility of ctDNA for RCC. Fifty-three patients histologically diagnosed with clear cell RCC were enrolled. Targeted sequencing was carried out using plasma cell-free DNA...

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PMID: 30536551
DOI: 10.1111/cas.13906

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