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Article

Optimized targeted sequencing of cell-free plasma DNA from bladder cancer patients.

Scientific reports - 30 Jan 2018

Christensen Emil, Nordentoft Iver, Vang Søren, Birkenkamp-Demtröder Karin, Jensen Jørgen Bjerggaard, Agerbæk Mads, Pedersen Jakob Skou, Dyrskjøt Lars

Abstract excerpt

Analysis of plasma cell-free DNA (cfDNA) may provide important information in cancer research, though the often small fraction of DNA originating from tumor cells makes the analysis technically challenging. Digital droplet PCR (ddPCR) has been utilized extensively as sufficient technical performance is easily achieved, but analysis is restricted to few mutations. Next generation sequencing (NGS) approaches have...

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Identifiers

PMID: 29382943
DOI: 10.1038/s41598-018-20282-8
PMCID: PMC5789978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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