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Article

Identification of <i>NTRK</i> fusions in pediatric mesenchymal tumors

18 Jan 2017

Abstract excerpt

BACKGROUND: NTRK fusions are known oncogenic drivers and have recently been effectively targeted by investigational agents in adults. We sought to assess the frequency of NTRK fusions in a large series of pediatric and adolescent patients with advanced cancers. PROCEDURE: Genomic profiles from 2,031 advanced cancers from patients less than 21 years old who were assayed with comprehensive genomic profiling were...

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PMID: 28097808
DOI: 10.1002/pbc.26433

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