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Article

Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci

26 Nov 2018

Abstract excerpt

Streptococcus pneumoniae serotype 3 remains a significant cause of morbidity and mortality worldwide, despite inclusion in the 13-valent pneumococcal conjugate vaccine (PCV13). Serotype 3 increased in carriage since the implementation of PCV13 in the USA, while invasive disease rates remain unchanged. We investigated the persistence of serotype 3 in carriage and disease, through genomic analyses of a global...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30475919
DOI: 10.1371/journal.ppat.1007438

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