Article
Evolution of Streptococcus pneumoniae Serotype 3 in England and Wales: A Major Vaccine Evader
25 Oct 2019
Abstract excerpt
serotype 3 remains a major cause of invasive pneumococcal disease in England and Wales. Previous studies have indicated that there are distinct lineages within serotype 3 clonal complex 180 and the clade distributions have shifted in recent years with the emergence of clade II. We undertook whole genome sequencing and genomic analysis of 616 serotype 3 isolates from England and Wales between 2003 and 2018,...
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