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Population genomics of pneumococcal carriage in Massachusetts children following introduction of PCV-13.

Microbial genomics - 1 Feb 2019

Mitchell Patrick K, Azarian Taj, Croucher Nicholas J, Callendrello Alanna, Thompson Claudette M, Pelton Stephen I, Lipsitch Marc, Hanage William P

Abstract excerpt

The 13-valent pneumococcal conjugate vaccine (PCV-13) was introduced in the United States in 2010. Using a large paediatric carriage sample collected from shortly after the introduction of PCV-7 to several years after the introduction of PCV-13, we investigate alterations in the composition of the pneumococcal population following the introduction of PCV-13, evaluating the extent to which the post-vaccination...

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Identifiers

PMID: 30777813
DOI: 10.1099/mgen.0.000252
PMCID: PMC6421351

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