Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CC180 clade dynamics do not universally explain Streptococcus pneumoniae serotype 3 persistence post-vaccine: a global comparative population genomics study

3 Jun 2025

Abstract excerpt

BACKGROUND: Clonal complex 180 (CC180) is currently the major clone of serotype 3 Streptococcus pneumoniae (Spn) causing disease among children and adults worldwide. The 13-valent pneumococcal conjugate vaccine (PCV13) does not have significant efficacy against serotype 3 despite polysaccharide inclusion in the vaccine. It was hypothesized that PCV13 may effectively control Clade I of CC180 but that Clades III...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Infections and Vaccines
Share to Pneumonia and Respiratory Infections
Share to Respiratory viral infections research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40472804
DOI: 10.1016/j.ebiom.2025.105781

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CC180 clade dynamics do not universally explain Streptococcus pneumoniae serotype 3 persistence post-vaccine: a global comparative population genomics studyPMID 40472804Read ↗

CC180 clade dynamics do not universally explain<i>Streptococcus pneumoniae</i>serotype 3 persistence post-vaccine: a global comparative population genomics studySemantic proximity Read ↗

Global emergence and population dynamics of divergent serotype 3 CC180 pneumococciSemantic proximity Read ↗

Global emergence and population dynamics of divergent serotype 3 CC180 pneumococciSemantic proximity Read ↗

Evolution of Streptococcus pneumoniae Serotype 3 in England and Wales: A Major Vaccine EvaderSemantic proximity Read ↗

<i>Streptococcus pneumoniae</i>serotype 3 population structure in the era of conjugate vaccines, 2001-2018Semantic proximity Read ↗

Clonal Expansion of a Streptococcus pneumoniae Serotype 3 Capsule Variant Sequence Type 700 With Enhanced Vaccine Escape Potential After 13-Valent Pneumococcal Conjugate Vaccine Introduction.Semantic proximity Read ↗

Upsurge of pneumococcal clade I-α/CC180 serotype 3 and its association with a LytA mutation linked to immune evasion and disease potential: an observational and experimental study.Semantic proximity Read ↗

Population genomics of pneumococcal carriage in Massachusetts children following introduction of PCV-13.Semantic proximity Read ↗

Dominant role of nucleotide substitution in the diversification of serotype 3 pneumococci over decades and during a single infection.Semantic proximity Read ↗

Post-vaccine epidemiology of serotype 3 pneumococci identifies transformation inhibition through prophage-driven alteration of a non-coding RNASemantic proximity Read ↗

Global pneumococcal sequence cluster lineage for invasive pneumococcal isolates in Denmark from summer 2019 to 2023Semantic proximity Read ↗

Using genomics to examine the persistence of Streptococcus pneumoniae serotype 19A in Ireland and the emergence of a sub-clade associated with vaccine failuresSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.