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Article

Gastrointestinal bleeding with severe mucosal involvement in a patient with generalized pustular psoriasis without IL 36 RN mutation

26 Nov 2018

Abstract excerpt

Generalized pustular psoriasis (GPP) is a systemic inflammatory disease that presents with erythema and sterile pustules, pathologically characterized by Kogoj's spongiform pustules. GPP is sometimes accompanied by mucosal involvement, and the most common lesion is on the tongue. IL36RN mutation was found to contribute to the pathogenesis of GPP especially in patients who develop GPP without a past medical...

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PMID: 30474867
DOI: 10.1111/1346-8138.14711

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