Article
Mutations in IL36RN are associated with geographic tongue.
Human genetics - 1 Feb 2017
Liang Jianying, Huang Peichen, Li Huaguo, Zhang Jia, Ni Cheng, Wang Yirong, Shen Jinwen, Li Chunxiao, Kang Lu, Chen Jie, Zhang Hui, Wang Zhen, Zhang Zhen, Li Ming, Yao Zhirong
Abstract excerpt
Geographic tongue (GT) is a benign inflammatory disorder of unknown etiology. Epidemiology and histopathology in previous studies found that generalized pustular psoriasis (GPP) is a factor associated with GT, but the molecular mechanism remains obscure. To investigate the mechanism of GT, with and without GPP, three cohorts were recruited to conduct genotyping of IL36RN, which is the causative gene of GPP. In a...
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