Article
IL36RN mutations in generalized pustular psoriasis: just the tip of the iceberg?
The Journal of investigative dermatology - 1 Nov 2013
Capon Francesca
Abstract excerpt
As IL36RN mutations are a cause of generalized pustular psoriasis (GPP), three recent investigations attempted to correlate the IL36RN genotype with GPP clinical presentations. These studies found that IL36RN mutations account for only a fraction of GPP cases presenting with concomitant psoriasis vulgaris (PV; common or typical psoriasis). Pathogenic alleles were also found in control populations, indicating that...
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