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Article

Genes and environment in chronic kidney disease hotspots

17 Nov 2018

Abstract excerpt

PURPOSE OF REVIEW: Chronic kidney disease (CKD) can cluster in geographic locations or in people of particular genetic ancestries. We explore APOL1 nephropathy and Balkan nephropathy as examples of CKD clustering that illustrate genetics and environment conspiring to cause high rates of kidney disease. Unexplained hotspots of kidney disease in Asia and Central America are then considered from the perspective of...

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PMID: 30451737
DOI: 10.1097/mnh.0000000000000470

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