Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Age stratification corrects bias in estimated hazard of APOE genotype for Alzheimer's disease

1 Jan 2018

Abstract excerpt

INTRODUCTION: The apolipoprotein E (APOE) e4 allele is a major genetic risk factor of late-onset Alzheimer's disease. However, its interaction with two other canonical risk factors, age and sex, is not clear. Previous studies have reported conflicting results on its differential effects in men and women, its association with young-onset AD before the age of 65 years, and its significance in genetic admixture...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Dementia and Cognitive Impairment Research
Share to Renin-Angiotensin System Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30450407
DOI: 10.1016/j.trci.2018.09.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Age stratification corrects bias in estimated hazard of APOE genotype for Alzheimer's diseasePMID 30450407Read ↗

Age‐dependent effects of <i>APOE</i> ε4 in preclinical Alzheimer's diseaseSemantic proximity Read ↗

Personalized genetic assessment of age associated Alzheimer’s disease riskSemantic proximity Read ↗

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.Semantic proximity Read ↗

APOE genotype effects on Alzheimer's disease onset and epidemiology.Semantic proximity Read ↗

Analyzing age-specific genetic effects on human extreme age survival in cohort-based longitudinal studies.Semantic proximity Read ↗

Greater Effect of Polygenic Risk Score for Alzheimer’s Disease Among Younger Cases who are Apolipoprotein E-ε4 CarriersSemantic proximity Read ↗

Apolipoprotein E4 allele and Alzheimer disease: examination of allelic association and effect on age at onset in both early- and late-onset cases.Semantic proximity Read ↗

<i>APOE</i> ε4 effects on hippocampal atrophy in the healthy elderly reflect future cognitive declineSemantic proximity Read ↗

Apolipoprotein E moderates the association between Non-<i>APOE</i>Polygenic Risk Score for Alzheimer’s Disease and Aging on Preclinical Cognitive FunctionSemantic proximity Read ↗

[Correlation between Apolipoprotein E polymorphism and age at onset of Alzheimer's disease in a Chinese Han population].Semantic proximity Read ↗

Association of APOE Genotype With Heterogeneity of Cognitive Decline Rate in Alzheimer Disease.Semantic proximity Read ↗

Longitudinal Modeling of Age-Related Memory Decline and the<i>APOE</i>ε4 EffectSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.