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Article

Cellular radiosensitivity: How much better do we understand it?

1 Dec 2009

Abstract excerpt

PURPOSE: Ionising radiation exposure gives rise to a variety of lesions in DNA that result in genetic instability and potentially tumourigenesis or cell death. Radiation extends its effects on DNA by direct interaction or by radiolysis of H(2)O that generates free radicals or aqueous electrons capable of interacting with and causing indirect damage to DNA. While the various lesions arising in DNA after radiation...

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Identifiers

PMID: 19995233
DOI: 10.3109/09553000903261263

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