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Article

MiR-10a and HOXB4 are overexpressed in atypical myeloproliferative neoplasms

12 Nov 2018

Abstract excerpt

Atypical Myeloproliferative Neoplasms (aMPN) share characteristics of MPN and Myelodysplastic Syndromes. Although abnormalities in cytokine signaling are common in MPN, the pathophysiology of atypical MPN still remains elusive. Since deregulation of microRNAs is involved in the biology of various cancers, we studied the miRNome of aMPN patients. MiRNome and mutations in epigenetic regulator genes ASXL1 , TET2 ,...

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PMID: 30419846
DOI: 10.1186/s12885-018-4993-2

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