Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes.

EBioMedicine - 1 Jan 2023

Wu Fan, Yin Yi-Yun, Fan Wen-Hua, Zhai You, Yu Ming-Chen, Wang Di, Pan Chang-Qing, Zhao Zheng, Li Guan-Zhang, Zhang Wei

Abstract excerpt

BACKGROUND: Human oligodendroglioma presents as a heterogeneous disease, primarily characterized by the isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion. Therapy development for this tumor is hindered by incomplete knowledge of somatic driving alterations and suboptimal disease classification. We herein aim to identify intrinsic molecular subtypes through integrated analysis of transcriptome, genome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 1

Share to Isocitrate Dehydrogenase

Share to Mutation

Share to Oligodendroglioma

Share to Prognosis

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 36525723
DOI: 10.1016/j.ebiom.2022.104410
PMCID: PMC9772571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes.PMID 36525723Read ↗

Integrated multi-omics analysis of oligodendroglial tumours identifies three subgroups of 1p/19q co-deleted gliomasSemantic proximity Read ↗

Molecular landscape of IDH-mutant astrocytoma and oligodendroglioma grade 2 indicate tumor purity as an underlying genomic factor.Semantic proximity Read ↗

Emerging biomarkers in anaplastic oligodendroglioma: implications for clinical investigation and patient management.Semantic proximity Read ↗

The Cancer Genome Atlas expression profiles of low-grade gliomas.Semantic proximity Read ↗

Comprehensive Molecular Analyses of a Novel Mutational Signature Classification System with Regard to Prognosis, Genomic Alterations, and Immune Landscape in GliomaSemantic proximity Read ↗

Immune landscape of isocitrate dehydrogenase stratified human gliomasSemantic proximity Read ↗

Oligodendroglioma: pathology, molecular mechanisms and markersSemantic proximity Read ↗

Potential of IDH mutations as immunotherapeutic targets in gliomas: a review and meta-analysis.Semantic proximity Read ↗

DNA Methylation-Based Deconvolution Sheds Light on Glioblastoma Heterogeneity and Cell-Type Composition Associated with Patient SurvivalSemantic proximity Read ↗

Multi-faceted computational assessment of risk and progression in oligodendroglioma implicates NOTCH and PI3K pathwaysSemantic proximity Read ↗

Immune cell deconvolution of bulk DNA methylation data reveals an association with methylation class, key somatic alterations, and cell state in glial/glioneuronal tumorsSemantic proximity Read ↗

[Basic principles of diagnosis and treatment of gliomas].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.