Article

Radiation-induced heart energy metabolism dysfunction leads to heart fibrosis

2020-12-15

Abstract excerpt

<title>Abstract</title> <p>Thoracic radiotherapy increases the risk of radiation-induced heart disease (RIHD), but its molecular mechanisms are not fully understood. We aimed to explore the effects of radiation on the mouse heart using high-throughput proteomics. An RIHD mouse model was established by exposing the whole heart to 16 Gy high-energy X-rays, and cardiac injuries were verified by cardiac echocardiogra...

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Literature Corpus work: 032ca844-c978-58d9-acad-c7b1c09d2df2
DOI: 10.21203/rs.3.rs-127935/v1

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