Article
Targeting oncogenic kinases: Insights on FDA approved tyrosine kinase inhibitors.
European journal of pharmacology - 5 May 2024
Hussain Sahil, Mursal Mohd, Verma Garima, Hasan Syed Misbahul, Khan Mohemmed Faraz
Abstract excerpt
Protein kinases play pivotal roles in various biological functions, influencing cell differentiation, promoting survival, and regulating the cell cycle. The disruption of protein kinase activity is intricately linked to pathways in tumor development. This manuscript explores the transformative impact of protein kinase inhibitors on cancer therapy, particularly their efficacy in cases driven by targeted mutations....
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