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Article

HOPX homeobox methylation in differentiated thyroid cancer and its clinical relevance

26 Oct 2018

Abstract excerpt

BACKGROUND: The inactivation of the tumor-suppressor homeodomain-only protein X (HOPX) usually involves promoter methylation in several cancer types. This study aimed to investigate the HOPX-β mRNA expression and promoter methylation and their clinical relevance in differentiated thyroid cancer (DTC). PATIENTS AND METHODS: Clinicopathological data and paraffin-embedded thyroid tumor tissues from 21 patients with...

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Share to Epigenetics and DNA Methylation
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PMID: 30400039
DOI: 10.1530/ec-18-0380

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