Article
Epigenetic-related gene expression profile in medullary thyroid cancer revealed the overexpression of the histone methyltransferases EZH2 and SMYD3 in aggressive tumours.
Molecular and cellular endocrinology - 5 Jul 2014
Sponziello Marialuisa, Durante Cosimo, Boichard Amelie, Dima Mariavittoria, Puppin Cinzia, Verrienti Antonella, Tamburrano Giulia, Di Rocco Giorgio, Redler Adriano, Lacroix Ludovic, Bidart Jean-Michel, Schlumberger Martin, Damante Giuseppe, Russo Diego, Filetti Sebastiano
Abstract excerpt
Epigenetic control of gene expression plays a major influence in the development and progression of many cancer types. Aim of the present study was to investigate the expression of epigenetic regulators in a large cohort of medullary thyroid carcinomas (MTC), correlating the data with the clinica...
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