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MSH2 Gene Point Mutations Are Not Antifungal Resistance Markers in Candida glabrata

20 Dec 2018

Abstract excerpt

The high rates of antifungal resistance in Candida glabrata may be facilitated by the presence of alterations in the MSH2 gene. We aimed to study the sequence of the MSH2 gene in 124 invasive C. glabrata isolates causing incident episodes of candidemia ( n = 81), subsequent candidemia episodes ( n = 9), endocarditis ( n = 2), and in vitro -generated echinocandin-resistant isolates ( n = 32) and assessed its...

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PMID: 30397068
DOI: 10.1128/aac.01876-18

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