Article
Absence of Azole or Echinocandin Resistance in Candida glabrata Isolates in India despite Background Prevalence of Strains with Defects in the DNA Mismatch Repair Pathway.
Antimicrobial agents and chemotherapy - 1 Jun 2018
Singh Ashutosh, Healey Kelley R, Yadav Priyanka, Upadhyaya Gargi, Sachdeva Neelam, Sarma Smita, Kumar Anil, Tarai Bansidhar, Perlin David S, Chowdhary Anuradha
Abstract excerpt
Candida glabrata infections are increasing worldwide and exhibit greater rates of antifungal resistance than those with other species. DNA mismatch repair (MMR) gene deletions, such as msh2Δ, in C. glabrata resulting in a mutator phenotype have recently been reported to facilitate rapid acquisition of antifungal resistance. This study determined the antifungal susceptibility profiles of 210 C. glabrata isolates...
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