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Article

von Willebrand factor clearance – biological mechanisms and clinical significance

1 Oct 2018

Abstract excerpt

The mechanisms involved in regulating von Willebrand factor (VWF) clearance remain poorly understood. However recent studies have shown that macrophages play a critical role in regulating the half-life of VWF, and have identified specific lectin (including asialoglycoprotein, macrophage galactose-type lectin, Sigec-5 and C-type lectin domain family 4 member M) and scavenger receptors (including low-density...

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PMID: 30378120
DOI: 10.1111/bjh.15565

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