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Survival of von Willebrand factor released following DDAVP in a type 1 von Willebrand disease cohort: influence of glycosylation, proteolysis and gene mutations.

Thrombosis and haemostasis - 1 May 2008

Millar Carolyn M, Riddell Anne F, Brown Simon A, Starke Richard, Mackie Ian, Bowen Derrick J, Jenkins P Vincent, van Mourik Jan A

Abstract excerpt

Reduced plasma survival of von Willebrand factor (VWF) may contribute towards the pathogenesis of type 1 von Willebrand disease (VWD). However, little is known about mechanism(s) of VWF clearance and factors that may affect it. The half-life of VWF-related parameters following the administration of DDAVP was measured in 26 patients with type 1 VWD and 10 haemophilia A controls. Binding of lectins Ricinus communis...

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Identifiers

PMID: 18449422
DOI: 10.1160/TH07-09-0565

Genes

VWF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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