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Article

Clearance of von Willebrand factor

1 Jan 2008

Abstract excerpt

The life cycle of von Willebrand factor (VWF) comprises a number of distinct steps, ranging from the controlled expression of the VWF gene in endothelial cells and megakaryocytes to the removal of VWF from the circulation. The various aspects of VWF clearance have been the objects of intense research in the last few years, stimulated by observations that VWF clearance is a relatively common component of the...

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PMID: 18278174
DOI: 10.1160/th07-10-0629

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