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Article

Novel immune signatures associated with dysplastic naevi and primary cutaneous melanoma in human skin

16 Oct 2018

Abstract excerpt

Dysplastic naevi (DN) are benign lesions with atypical features intermediate between that of common melanocytic naevi (CMN) and malignant melanoma (MM). Debate remains over whether DN represent progressive lesions from CMN. Through gene expression profiling and analysis of molecular gene signatures, our study revealed progressive increases in immune activation and regulation, along with pathways implicated in...

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Share to Cutaneous Melanoma Detection and Management
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30326165
DOI: 10.1111/exd.13805

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