Article
Expression Profiling Reveals Novel Pathways in the Transformation of Melanocytes to Melanomas
1 Aug 2004
Abstract excerpt
Affymetrix and spotted oligonucleotide microarrays were used to assess global differential gene expression comparing normal human melanocytes with six independent melanoma cell strains from advanced lesions. The data, validated at the protein level for selected genes, confirmed the overexpression in melanoma cells relative to normal melanocytes of several genes in the growth factor/receptor family that confer...
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