Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Raman micro-spectroscopy monitors acquired resistance to targeted cancer therapy at the cellular level

9 Oct 2018

Abstract excerpt

Monitoring the drug efficacy or resistance in vitro is usually carried out by measuring the response of single few proteins. However, observation of single proteins instead of an integral cell response may lead to results that are not consistent with patient's response to a drug. We present a Raman spectroscopic method that detects the integral cell response to drugs such as tyrosine kinase inhibitors (TKIs)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Melanoma and MAPK Pathways
Share to Silymarin and Mushroom Poisoning

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 30323297
DOI: 10.1038/s41598-018-33682-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Raman micro-spectroscopy monitors acquired resistance to targeted cancer therapy at the cellular levelPMID 30323297Read ↗

Label-Free Raman Spectroscopic Imaging Monitors the Integral Physiologically Relevant Drug Responses in Cancer Cells.Semantic proximity Read ↗

In vitro prediction of the efficacy of molecularly targeted cancer therapy by Raman spectral imaging.Semantic proximity Read ↗

In Situ Single Cell Proteomics Reveals Circulating Tumor Cell Heterogeneity during TreatmentSemantic proximity Read ↗

Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes.Semantic proximity Read ↗

A multiparametric fluorescent visualization approach for detecting drug resistance in living cancer cells.Semantic proximity Read ↗

Facilitated Transport of EGFR Inhibitors Plays an Important Role in Their Cellular Uptake.Semantic proximity Read ↗

Nanoscale Mapping of EGFR and c‑MET Protein Environments on Lung Cancer Cell Surfaces via Therapeutic Antibody Photocatalyst ConjugatesSemantic proximity Read ↗

Detection of EGFR mutation in plasma using multiplex allele-specific PCR (MAS-PCR) and surface enhanced Raman spectroscopy.Semantic proximity Read ↗

Imaging vs Nonimaging Raman Spectroscopy for High-Throughput Single-Cell Phenotyping.Semantic proximity Read ↗

Nanoplasmonic Detection of EGFR Mutations Based on Extracellular Vesicle-Derived EGFR-Drug Interaction.Semantic proximity Read ↗

EGFR signaling and pharmacology in oncology revealed with innovative BRET-based biosensorsSemantic proximity Read ↗

DNA Fingerprint Analysis of Raman Spectra Captures Global Genomic Alterations in Imatinib-Resistant Chronic Myeloid Leukemia: A Potential Single Assay for Screening Imatinib Resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.