Article
A multiparametric fluorescent visualization approach for detecting drug resistance in living cancer cells.
Talanta - 1 Jul 2023
Zhou Zhilan, Wang Ya, Shao Zhengtao, Zhang Guixi, Jiang Hang, Tang Yiyuan, Huang Zening, Zhu Yingdi, Li Juan
Abstract excerpt
Drug resistance is a worldwide health care crisis which impedes disease treatment and increases financial burden, especially for its multifactorial nature and high complexity. Herein, we developed a multiparametric approach to visualize and detect drug resistance in living cancer cells, through the combination of DNA-templated covalent protein labeling strategy and fluorescent resonance energy transfer technique....
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