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Article

Identification of a Prognostic Hypoxia-Associated Gene Set in IDH-Mutant Glioma

25 Sept 2018

Abstract excerpt

Glioma growth is often accompanied by a hypoxic microenvironment favorable for the induction and maintenance of the glioma stem cell (GSC) phenotype. Due to the paucity of cell models of Isocitrate Dehydrogenase 1 mutant (IDH1mut) GSCs, biology under hypoxic conditions has not been sufficiently studied as compared to IDH1 wildtype (IDH1wt) GSCs. We therefore grew well-characterized IDH1mut (n = 4) and IDH1wt (n =...

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PMID: 30257451
DOI: 10.3390/ijms19102903

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