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Article

Prognostic value and immune cell infiltration of hypoxic phenotype-related gene signatures in glioblastoma microenvironment.

Journal of cellular and molecular medicine - 1 Nov 2020

Xiao Kai, Tan Jun, Yuan Jian, Peng Gang, Long Wenyong, Su Jun, Xiao Yao, Xiao Qun, Wu Changwu, Qin Chaoying, Hu Lili, Liu Kaili, Liu Shunlian, Zhou Hao, Ning Yichong, Ding Xiaofeng, Liu Qing

Abstract excerpt

Glioblastoma (GBM) is a malignant intracranial tumour with the highest proportion and lethality. It is characterized by invasiveness and heterogeneity. However, the currently available therapies are not curative. As an essential environmental cue that maintains glioma stem cells, hypoxia is considered the cause of tumour resistance to chemotherapy and radiation. Growing evidence shows that immunotherapy focusing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33009892
DOI: 10.1111/jcmm.15939
PMCID: PMC7701576

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