Article
High frequency of unequal recombination in pseudoautosomal region shown by proviral insertion in transgenic mouse.
Nature - 1 Jan 2000
Harbers K, Soriano P, Müller U, Jaenisch R
Abstract excerpt
The mammalian X and Y chromosomes, in contrast to the autosomes, pair during male meiosis only near the telomeres. Alleles localized in this region can undergo reciprocal exchange during meiosis. Because such sequences do not show strict sex-linked inheritance, they have been termed pseudoautosomal. In man, several DNA sequences have been described which show pseudoautosomal transmission and which are localized...
Topics
- Animals
- Blastocyst
- Cloning, Molecular
- Crosses, Genetic
- DNA Restriction Enzymes
- DNA Transposable Elements
- Female
- Genes, Viral
- Genotype
- Male
- Mice
- Mice, Inbred BALB C
