Article
A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes.
Nature - 1 Jan 2000
Rouyer F, Simmler M C, Johnsson C, Vergnaud G, Cooke H J, Weissenbach J
Abstract excerpt
Three independent pseudoautosomal loci are linked to sex determination at frequencies which define a gradient of linkage. The segregation patterns of these loci indicate that X/Y recombination results from a single obligatory meiotic crossing-over in the pseudoautosomal region. Recombination in male germ cells in the terminal regions of the short arms of the X and Y chromosomes in 10-fold greater than between the...
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