Identification of a second pseudoautosomal region near the Xq and Yq telomeres.

doi:10.1126/science.1465614

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Article

Identification of a second pseudoautosomal region near the Xq and Yq telomeres.

Science (New York, N.Y.) - 11 Dec 1992

Freije D, Helms C, Watson M S, Donis-Keller H

Abstract excerpt

The telomeres of Xq and Yq have been observed to associate during meiosis, and in rare cases a short synaptonemal complex is present. Molecular cloning of loci from Xqter and Yqter has revealed that their sequence homology extends over 400 kilobases, which suggests the possibility of genetic exchange. This hypothesis was tested by the development of two highly informative microsatellite markers from yeast...

Topics

Alleles
Animals
Base Sequence
Cell Line
Chromosome Banding
Chromosome Mapping
Chromosomes, Fungal
Cloning, Molecular
DNA
Factor VIII
Female
Gene Conversion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Linkage

Haplotypes

Humans

Hybrid Cells

Male

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 1465614
DOI: 10.1126/science.1465614

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1465614-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Identification of a second pseudoautosomal region near the Xq and Yq telomeres.PMID 1465614Read ↗

Recombination and allelic association in the Xq/Yq homology region.Semantic proximity Read ↗

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Exchange of terminal portions of X- and Y-chromosomal short arms in human XX males.Semantic proximity Read ↗

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