Article
JUNB, DUSP2, SGK1, SOCS1 and CREBBP are frequently mutated in T-cell/histiocyte-rich large B-cell lymphoma.
Haematologica - 1 Feb 2019
Schuhmacher Bianca, Bein Julia, Rausch Tobias, Benes Vladimir, Tousseyn Thomas, Vornanen Martine, Ponzoni Maurilio, Thurner Lorenz, Gascoyne Randy, Steidl Christian, Küppers Ralf, Hansmann Martin-Leo, Hartmann Sylvia
Abstract excerpt
T-cell/histiocyte-rich large B-cell lymphoma is a rare aggressive lymphoma showing histopathological overlap with nodular lymphocyte-predominant Hodgkin lymphoma. Despite differences in tumor microenvironment and clinical behavior, the tumor cells of both entities show remarkable similarities, suggesting that both lymphomas might represent a spectrum of the same disease. To address this issue, we investigated...
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