Article
Newly identified mechanisms in B-cell non-Hodgkin lymphomas uncovered by next-generation sequencing.
Seminars in hematology - 1 Oct 2013
Morin Ryan D, Gascoyne Randy D
Abstract excerpt
Application of molecular techniques to study the genetics and gene expression alterations in non-Hodgkin lymphomas (NHLs) has revealed examples of common genetic events shared across individual disease types as well as extensive heterogeneity within specific diseases. For example, diffuse large B-cell lymphoma (DLBCL) can be effectively divided into two broad molecular subgroups in which genetic changes unique to...
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