Article
Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria.
PLoS pathogens - 1 Sept 2018
Passmore Ian J, Letertre Marine P M, Preston Mark D, Bianconi Irene, Harrison Mark A, Nasher Fauzy, Kaur Harparkash, Hong Huynh A, Baines Simon D, Cutting Simon M, Swann Jonathan R, Wren Brendan W, Dawson Lisa F
Abstract excerpt
Clostridium difficile is a Gram-positive spore-forming anaerobe and a major cause of antibiotic-associated diarrhoea. Disruption of the commensal microbiota, such as through treatment with broad-spectrum antibiotics, is a critical precursor for colonisation by C. difficile and subsequent disease. Furthermore, failure of the gut microbiota to recover colonisation resistance can result in recurrence of infection....
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