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Assessing the role of p-cresol tolerance in Clostridium difficile

14 May 2008

Abstract excerpt

Clostridium difficile is an important nosocomial pathogen, resulting in antibiotic-associated disease ranging from mild diarrhoea to the life-threatening pseudomembranous colitis. Upon antibiotic exposure, it is believed that the normal bowel microflora of patients is disrupted, allowing C. difficile to proliferate. Significantly, C. difficile is among only a few bacteria able to ferment tyrosine to p-cresol, a...

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PMID: 18480332
DOI: 10.1099/jmm.0.47744-0

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