Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mapping Exchangeable Protons to Monitor Protein Alterations in the Brain of an Alzheimer's Disease Mouse Model by Using MRI.

Current Alzheimer research - 1 Jan 2018

Jahng Geon-Ho, Choi Wonmin, Chung Julius J, Kim Sang T, Rhee Hak Y

Abstract excerpt

OBJECTIVE: The study aimed to investigate exchangeable proton signals of Aβ proteins of the brains of Alzheimer's disease (AD) model mice by using a chemical exchange-sensitive spin-lock (CESL) MR imaging technique. METHOD: Eight non-transgenic (Tg) mice (5 young and 3 old) and twelve Tg-APPswe/PSdE9 mice (5 young and 7 old) were used in this study. CESL Z-spectra were obtained by using two saturation powers,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Amides
Share to Amyloid beta-Protein Precursor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain Mapping

Share to Image Processing, Computer-Assisted

Share to Magnetic Resonance Imaging

Share to Presenilin-1

Share to Protons

Source

Identifiers

PMID: 30207233
DOI: 10.2174/1567205015666180911143518

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mapping Exchangeable Protons to Monitor Protein Alterations in the Brain of an Alzheimer's Disease Mouse Model by Using MRI.PMID 30207233Read ↗

Proton and Phosphorus Magnetic Resonance Spectroscopy of a Mouse Model of Alzheimer's DiseaseSemantic proximity Read ↗

1H NMR metabolomic signatures in five brain regions of the AβPPswe Tg2576 mouse model of Alzheimer's disease at four ages.Semantic proximity Read ↗

Molecular imaging of butyrylcholinesterase associated with amyloid-β plaques distinguishes 5XFAD from wild-type miceSemantic proximity Read ↗

In vivo 1H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatment.Semantic proximity Read ↗

¹H- and ¹³C-NMR spectroscopy of Thy-1-APPSL mice brain extracts indicates metabolic changes in Alzheimer's disease.Semantic proximity Read ↗

Treatment effects in a transgenic mouse model of Alzheimer's disease: a magnetic resonance spectroscopy study after passive immunization.Semantic proximity Read ↗

Evaluation of B0-correction of relative CBF maps using tagging distance dependent Z-spectrum (TADDZ).Semantic proximity Read ↗

Absence of changes in GABA concentrations with age and gender in the human anterior cingulate cortex: A MEGA‐PRESS study with symmetric editing pulse frequencies for macromolecule suppressionSemantic proximity Read ↗

Preferred features of a fluorine-19 MRI probe for amyloid detection in the brain.Semantic proximity Read ↗

Chronic BACE-1 Inhibitor Administration in TASTPM Mice (APP KM670/671NL and PSEN1 M146V Mutation): An EEG Study.Semantic proximity Read ↗

Quantitative MRI reveals aging-associated T2 changes in mouse models of Alzheimer's disease.Semantic proximity Read ↗

Superparamagnetic nanoparticle-enhanced MRI of Alzheimer's disease plaques and activated microglia in 3X transgenic mouse brains: Contrast optimization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.