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Article

Treatment effects in a transgenic mouse model of Alzheimer's disease: a magnetic resonance spectroscopy study after passive immunization.

Neuroscience - 14 Feb 2014

Marjańska M, Weigand S D, Preboske G, Wengenack T M, Chamberlain R, Curran G L, Poduslo J F, Garwood M, Kobayashi D, Lin J C, Jack C R

Abstract excerpt

Despite the enormous public health impact of Alzheimer's disease (AD), no disease-modifying treatment has yet been proven to be efficacious in humans. A rate-limiting step in the discovery of potential therapies for humans is the absence of efficient non-invasive methods of evaluating drugs in animal models of disease. Magnetic resonance spectroscopy (MRS) provides a non-invasive way to evaluate the animals at...

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Identifiers

PMID: 24316473
DOI: 10.1016/j.neuroscience.2013.11.052
PMCID: PMC3928682

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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