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Serum Parathyroid Hormone, 25-Hydroxyvitamin D, and Risk of Alzheimer's Disease: A Mendelian Randomization Study.

Nutrients - 6 Sept 2018

Larsson Susanna C, Traylor Matthew, Markus Hugh S, Michaëlsson Karl

Abstract excerpt

We conducted Mendelian randomization analyses to investigate the associations of serum parathyroid hormone (S-PTH) and serum 25-hydroxyvitamin D (S-25OHD) concentrations with Alzheimer's disease (AD). Five and seven single nucleotide polymorphisms associated with S-PTH and S-25OHD concentrations, respectively, were used as instrumental variables. Data for AD were acquired from the International Genomics of...

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Identifiers

PMID: 30200567
DOI: 10.3390/nu10091243
PMCID: PMC6165184

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