Article
Impact of Serum Calcium Levels on Alzheimer's Disease: A Mendelian Randomization Study.
Journal of Alzheimer's disease : JAD - 1 Jan 2020
He Yating, Zhang Haihua, Wang Tao, Han Zhifa, Ni Qing-Bin, Wang Kun, Wang Longcai, Zhang Yan, Hu Yang, Jin Shuilin, Sun Bao-Liang, Liu Guiyou
Abstract excerpt
BACKGROUND: Altered calcium homeostasis is hypothesized to underlie Alzheimer's disease (AD). However, it remains unclear whether serum calcium levels are genetically associated with AD risk. OBJECTIVE: To develop effective therapies, we should establish the causal link between serum calcium levels and AD. METHODS: Here, we performed a Mendelian randomization study to investigate the causal association of...
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