Article
PDGF Restores the Defective Phenotype of Adipose-Derived Mesenchymal Stromal Cells from Diabetic Patients.
Molecular therapy : the journal of the American Society of Gene Therapy - 7 Nov 2018
Capilla-González Vivian, López-Beas Javier, Escacena Natalia, Aguilera Yolanda, de la Cuesta Antonio, Ruiz-Salmerón Rafael, Martín Franz, Hmadcha Abdelkrim, Soria Bernat
Abstract excerpt
Diabetes is a chronic metabolic disorder that affects 415 million people worldwide. This pathology is often associated with long-term complications, such as critical limb ischemia (CLI), which increases the risk of limb loss and mortality. Mesenchymal stromal cells (MSCs) represent a promising option for the treatment of diabetes complications. Although MSCs are widely used in autologous cell-based therapy, their...
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