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Single cell transcriptomics identifies adipose tissue CD271+ progenitors for enhanced angiogenesis in limb ischemia

2023-02-10

Abstract excerpt

<h4>SUMMARY</h4> Therapeutic angiogenesis using mesenchymal stem/stromal cell grafts have shown modest and controversial effects in preventing amputation for patients with critical limb ischemia. Through single-cell transcriptomic analysis of human tissues, we identified CD271 + progenitors specifically from subcutaneous adipose tissue (AT) as having the most prominent pro-angiogenic gene profile distinct from o...

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Identifiers and source

Literature Corpus work
9449b614-8052-57b1-aebc-432166275361
DOI
10.1101/2023.02.09.527726
Open publication

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Single cell transcriptomics identifies adipose tissue CD271+ progenitors for enhanced angiogenesis in limb ischemiaDOI 10.1101/2023.02.09.527726
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