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Article

Reversible secretome and signaling defects in diabetic mesenchymal stem cells from peripheral arterial disease patients.

Journal of vascular surgery - 1 Dec 2018

Chadid Tatiana, Morris Andrew, Surowiec Alexandra, Robinson Scott, Sasaki Maiko, Galipeau Jacques, Pollack Brian P, Brewster Luke P

Abstract excerpt

OBJECTIVE: Regenerative medicine seeks to stall or to reverse the pathologic consequences of chronic diseases. Many people with diabetes have peripheral arterial disease (PAD), which increases their already high risk of major amputation. Cellular therapies are a promising regenerative medicine approach to PAD that can be used to focally inject regenerative cells to endangered tissue beds. Mesenchymal stem cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30104096
DOI: 10.1016/j.jvs.2018.05.223
PMCID: PMC6252140

Genes

EGF
FGF2
MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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