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Article

The DNA repair transcriptome in severe COPD

6 Sept 2018

Abstract excerpt

Inadequate DNA repair is implicated in the pathogenesis of chronic obstructive pulmonary disease (COPD). However, the mechanisms that underlie inadequate DNA repair in COPD are poorly understood. We applied an integrative genomic approach to identify DNA repair genes and pathways associated with COPD severity.We measured the transcriptomic changes of 419 genes involved in DNA repair and DNA damage tolerance that...

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Share to Chronic Obstructive Pulmonary Disease (COPD) Research
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PMID: 30190272
DOI: 10.1183/13993003.01994-2017

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