PNPLA3 rs738409 Polymorphism Predicts Development and Severity of Hepatic Steatosis but Not Metabolic Syndrome in Celiac Disease.

doi:10.3390/nu10091239

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PNPLA3 rs738409 Polymorphism Predicts Development and Severity of Hepatic Steatosis but Not Metabolic Syndrome in Celiac Disease.

Nutrients - 5 Sept 2018

Tortora Raffaella, Rispo Antonio, Alisi Anna, Imperatore Nicola, Crudele Annalisa, Ferretti Francesca, Nobili Valerio, Miele Luca, Gerbino Nicolò, Caporaso Nicola, Morisco Filomena

Abstract excerpt

Metabolic syndrome (MS) and hepatic steatosis (HS) have been described in patients with celiac disease (CD) after starting a gluten-free diet (GFD), but data on predictive factors for these conditions are scarce. Recently, the patatin-like phospholipase domain-containing protein 3 (PNPLA3) rs738409 has been identified as a key factor for HS development in the general population. The aim of the study was to...

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PMID: 30189691
DOI: 10.3390/nu10091239
PMCID: PMC6163162

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