Article
Comparative genomics of Czech vaccine strains of Bordetella pertussis.
Pathogens and disease - 1 Oct 2018
Dienstbier Ana, Pouchnik Derek, Wildung Mark, Amman Fabian, Hofacker Ivo L, Parkhill Julian, Holubova Jana, Sebo Peter, Vecerek Branislav
Abstract excerpt
Bordetella pertussis is a strictly human pathogen causing the respiratory infectious disease called whooping cough or pertussis. B. pertussis adaptation to acellular pertussis vaccine pressure has been repeatedly highlighted, but recent data indicate that adaptation of circulating strains started already in the era of the whole cell pertussis vaccine (wP) use. We sequenced the genomes of five B. pertussis wP...
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