Article
Comparative genomics of whole-cell pertussis vaccine strains from India.
BMC genomics - 7 May 2020
Alai Shweta, Ghattargi Vikas C, Gautam Manish, Patel Krunal, Pawar Shrikant P, Dhotre Dhiraj P, Shaligram Umesh, Gairola Sunil
Abstract excerpt
BACKGROUND: Despite high vaccination coverage using acellular (ACV) and whole-cell pertussis (WCV) vaccines, the resurgence of pertussis is observed globally. Genetic divergence in circulating strains of Bordetella pertussis has been reported as one of the contributing factors for the resurgence of the disease. Our current knowledge of B. pertussis genetic evolution in circulating strains is mostly based on...
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